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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SRMS All Species: 12.73
Human Site: S465 Identified Species: 25.45
UniProt: Q9H3Y6 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H3Y6 NP_543013.1 488 54507 S465 L M L E C W R S S P E E R P S
Chimpanzee Pan troglodytes XP_525384 492 54970 S465 L M L E C W R S S P E E R P S
Rhesus Macaque Macaca mulatta XP_001114037 492 54778 S465 L M L E C W R S S P E E R P S
Dog Lupus familis XP_534478 629 68321 G602 L M L E C W K G S P A R R P A
Cat Felis silvestris
Mouse Mus musculus Q62270 496 55740 G469 L M V E C W K G S P E E R P T
Rat Rattus norvegicus Q62662 506 58147 V473 I M M E C W N V E P K Q R P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506797 498 57086 A471 I M L E C W K A N A E E R P T
Chicken Gallus gallus P42683 508 58121 E478 L M M Q C W K E Q P E E R P T
Frog Xenopus laevis P13116 532 59718 K500 L M F Q C W R K D P E E R P T
Zebra Danio Brachydanio rerio XP_698462 1009 113199 N979 I M L E C W K N K P E D R P T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V9J3 517 59051 K485 I M L E C W H K D P M R R P T
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001135852 530 59779 S497 I M L E C W K S K A M E R P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 94.3 59.9 N.A. 77.8 41.2 N.A. 68.6 40.7 39.6 23.4 N.A. 41.9 N.A. N.A. 42.4
Protein Similarity: 100 99.1 95.9 65.9 N.A. 85 55.5 N.A. 81.5 56.8 53.9 33.5 N.A. 57.6 N.A. N.A. 57.9
P-Site Identity: 100 100 100 66.6 N.A. 73.3 46.6 N.A. 60 60 66.6 60 N.A. 53.3 N.A. N.A. 60
P-Site Similarity: 100 100 100 80 N.A. 93.3 80 N.A. 93.3 86.6 80 93.3 N.A. 66.6 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 9 0 17 9 0 0 0 9 % A
% Cys: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 17 0 0 9 0 0 0 % D
% Glu: 0 0 0 84 0 0 0 9 9 0 67 67 0 0 0 % E
% Phe: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 17 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % H
% Ile: 42 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 50 17 17 0 9 0 0 0 0 % K
% Leu: 59 0 67 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 100 17 0 0 0 0 0 0 0 17 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 9 9 9 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 84 0 0 0 100 0 % P
% Gln: 0 0 0 17 0 0 0 0 9 0 0 9 0 0 0 % Q
% Arg: 0 0 0 0 0 0 34 0 0 0 0 17 100 0 0 % R
% Ser: 0 0 0 0 0 0 0 34 42 0 0 0 0 0 25 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % T
% Val: 0 0 9 0 0 0 0 9 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _